GPU Comparison

NVIDIA GB300vsAMD MI250X

Comprehensive comparison for AI, machine learning, and high-performance computing workloads.

vs
Performance Leader
NVIDIA

NVIDIA GB300

Blackwell Architecture

VRAM256 GB HBM3e
FP32 Performance120 TFLOPS
Memory Bandwidth10000 GB/s
TDP1200W
Avg. Price/Hour$4.25
AMD

AMD MI250X

CDNA 2 Architecture

VRAM128 GB HBM2e
FP32 Performance47.9 TFLOPS
Memory Bandwidth3277 GB/s
TDP560W
Avg. Price/Hour$1.35

Detailed Specifications

SpecificationNVIDIA GB300AMD MI250X
Architecture
Blackwell
CDNA 2
Release Year
2025
2021
VRAM
256 GB+100.0%
128 GB
Memory Type
HBM3e
HBM2e
Memory Bandwidth
10000 GB/s+205.2%
3277 GB/s
FP32 Performance
120 TFLOPS+150.5%
47.9 TFLOPS
FP16 Performance
240 TFLOPS+150.8%
95.7 TFLOPS
INT8 Performance
4800 TOPS+1153.3%
383 TOPS
Tensor Cores
20480
N/A
CUDA Cores
N/A
14080
TDP
1200W
560W
Form Factor
SXM
OAM
NVLink Support
Yes
No
Avg. Price/Hour
$4.25+214.8%
$1.35

Performance Breakdown

Compute Performance

Single-precision floating-point performance for general compute workloads

NVIDIA GB300
120TFLOPS
AMD MI250X
47.9TFLOPS

NVIDIA GB300 is 150.5% faster

AI Training Performance

Half-precision performance optimized for deep learning training

NVIDIA GB300
240TFLOPS
AMD MI250X
95.7TFLOPS

NVIDIA GB300 is 150.8% faster

AI Inference Performance

Integer performance for efficient model inference and deployment

NVIDIA GB300
4800TOPS
AMD MI250X
383TOPS

NVIDIA GB300 is 1153.3% faster

Memory Bandwidth

Data transfer speed between GPU and memory

NVIDIA GB300
10000GB/s
AMD MI250X
3277GB/s

NVIDIA GB300 is 205.2% faster

Performance

NVIDIA GB300

Memory

NVIDIA GB300

Value

AMD MI250X

Efficiency

NVIDIA GB300

Ideal Workloads

NVIDIA

NVIDIA GB300

Frontier AI Models
AGI Research
Exascale Computing
Multi-Modal AI
AMD

AMD MI250X

HPC
AI Training
Scientific Computing
Research

Cost Analysis

Hourly Rate

NVIDIA GB300
$4.25per hour
AMD MI250X
$1.35per hour
Savings with AMD MI250X$2.90 (68%)

Daily Cost

NVIDIA GB300
$102.00per day
AMD MI250X
$32.40per day
Savings with AMD MI250X$69.60 (68%)

Monthly Cost

NVIDIA GB300
$3102.50per month
AMD MI250X
$985.50per month
Savings with AMD MI250X$2117.00 (68%)

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Frequently Asked Questions

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